Hesselberth Lab

🤝 Our Mission. We are a collaborative research laboratory comprising RNA biologists, technology developers, and data analysts focused on discovering and translating fundamental principles of RNA regulation.
🧬 Core Research. Our major focus in the lab is to understand protein translation through the lens of transfer RNA (tRNA). Transfer RNAs link the RNA and protein worlds, and our new approaches enable us to tackle questions using new technologies, including the application of nanopore analysis to understand the dynamic use of tRNA by cells.
💊 Clinical Applications. Our newest efforts focus on RNA therapeutics. We work with clinicians at Children’s Hospital Colorado to develop RNA therapies for pediatric genetic diseases (lately focused on retinopathies), and with immunologists and virologists to develop new ways to manipulate and understand the mammalian immune system.
See our publications for more detail on these studies.
selected publications
news
May 2, 2025 |
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Feb 27, 2024 |
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Jul 9, 2023 |
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